- Undergraduate Education
- B.S./M.s. in Nutrition, University of Bonn, Germany, 1998
- Graduate Education
- Food Science and Nutrition, University of Florida, Gainesville, FL, 2004
- Postdoctoral training, Pharmaceutics, University of Florida, Gainesville, FL, 2006
- Excellence Award for Mentoring, Nutrition and Food Science Dept, Texas A&M University, 2011
- Excellence Award for Research, Nutrition and Food Science Dept, Texas A&M University, 2009
- ASN Mary Swartz Rose Young Investigator Award, 2009. American Society of Nutrition
- Courses Taught
- FSTC/NUTR 410: Nutritional Pharmacometrics of Food Compounds
- FSTC/NUTR 610: Nutritional Pharmacometrics of Food Compounds
- FSCT 314: Food Analysis
- NUTR/FSTC 489: Special Topics in Mediterranean Nutrition and Food processing in Italy, Summer A, even years
- NUTR/FSTC 489: Special Topics in Nutrition, Health and Food Processing in Honduras, Summer B, TBD
- NUTR/FSTC 489: Special Topics in Sustainable Nutrition and Food processing in Brazil, Summer A, odd years
- FSTC 481 Seminar for Seniors
Millions of Americans consume plant based foods, including dietary supplements and functional foods with the hope of preventing or even treating inflammation and associated chronic diseases. However, limited research is investigating safety, efficacy and dosing recommendations of non-nutrient bioactive food compounds. Hence, consumers, public health care, as well as food industry, have little to no guidance related to the efficacy, safety and intake recommendations. The overall objective of our laboratory is to investigate pharmacokinetics and pharmacodynamics of bioactive plant compounds and their metabolites and their anti-inflammatory efficacy in the reduction of risk factors for chronic degenerative diseases such as cancer and cardiovascular disease and their underlying molecular mechanisms. , pharmacokinetics and pharmacodynamics and underlying molecular mechanisms in a translational research approach (bench to bedside) of polyphenolics in fruits and vegetables in collaboration with an interdisciplinary research team. It is our long-term goal to contribute valuable information to the future development of dosing recommendation for these non-nutrient food components that meets the needs of public health care, patients and consumers, and food and dietary supplement industry.
Dr. Susanne Talcott’s research focuses on translational pharmacokinetics and pharmacodynamics of botanical compounds and their physiological metabolites related to inflammation, cancer prevention, and intestinal health with a focus on human clinical trials.
- Layosa, MAA, Lage, NN, Chew, BP, Atienza, L, Mertens-Talcott, S, Talcott, S et al.. Dark Sweet Cherry (Prunus avium) Phenolics Enriched in Anthocyanins Induced Apoptosis in MDA-MB-453 Breast Cancer Cells through MAPK-Dependent Signaling and Reduced Invasion via Akt and PLCγ-1 Downregulation. Nutr Cancer. 2020; :1-13. doi: 10.1080/01635581.2020.1817514. PubMed PMID:32924599 .
- Arbizu, S, Chew, B, Mertens-Talcott, SU, Noratto, G. Commercial whey products promote intestinal barrier function with glycomacropeptide enhanced activity in downregulating bacterial endotoxin lipopolysaccharides (LPS)-induced inflammation in vitro. Food Funct. 2020;11 (7):5842-5852. doi: 10.1039/d0fo00487a. PubMed PMID:32633745 .
- Noratto, G, Layosa, MA, Lage, NN, Atienza, L, Ivanov, I, Mertens-Talcott, SU et al.. Antitumor potential of dark sweet cherry sweet (Prunus avium) phenolics in suppressing xenograft tumor growth of MDA-MB-453 breast cancer cells. J. Nutr. Biochem. 2020;84 :108437. doi: 10.1016/j.jnutbio.2020.108437. PubMed PMID:32615370 .