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Chaodong Wu

Wu , Chaodong
Chaodong Wu
Professor and Faculty Fellow
217A Cater-Mattil
Undergraduate Education
Hubei University of Chinese Medicine (Wuhan), China. MD, Medicine, 1992
Graduate Education
Tongji Medical University (Wuhan), China. Master of Medical Science, 1995
Beijing Medical University, China. PhD in Medical Science, 1998
Junior Faculty Award, American Diabetes Association, 2010
Research Award, Minnesota Medical Foundation, 2004
Travel Award, Dept. of BMBB, the University of Minnesota, 2001
Pilot & Feasibility Research Award, Minnesota Obesity Center, 2002, 2005
Travel Award, The Center for Diabetes Research, University of Minnesota, 2001
Courses Taught
NUTR 470: Nutrition and Physiological Chemistry
NUTR 681: Nutrition Seminar

Research Interest

The long-term goal of Dr. Wu’s research program is to elucidate the mechanisms underlying the pathogenesis of obesity and overnutrition-associated metabolic diseases including insulin resistance, diabetes, and fatty liver disease so that novel dietary and/or pharmacological approaches can be developed for preventing and/or treating metabolic diseases. Using molecular, cellular, and integrative approaches, the Wu lab is focused on investigating the interaction between metabolism and inflammation.


Research Area

Obesity, insulin resistance, diabetes, and fatty liver disease


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  1. Kyritsi, K, Chen, L, O'Brien, A, Francis, H, Hein, TW, Venter, J et al.. Modulation of the TPH1/MAO-A/5HT/5HTR2A/2B/2C Axis Regulates Biliary Proliferation and Liver Fibrosis During Cholestasis. Hepatology. 2019; :. doi: 10.1002/hep.30880. PubMed PMID:31344280 .
  2. Cao, Y, Zhang, X, Wang, L, Yang, Q, Ma, Q, Xu, J et al.. PFKFB3-mediated endothelial glycolysis promotes pulmonary hypertension. Proc. Natl. Acad. Sci. U.S.A. 2019;116 (27):13394-13403. doi: 10.1073/pnas.1821401116. PubMed PMID:31213542 PubMed Central PMC6613097.
  3. Xu, J, Yang, Q, Zhang, X, Liu, Z, Cao, Y, Wang, L et al.. Endothelial adenosine kinase deficiency ameliorates diet-induced insulin resistance. J. Endocrinol. 2019; :. doi: 10.1530/JOE-19-0126. PubMed PMID:31189131 .
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