- Undergraduate Education
- Hubei University of Chinese Medicine (Wuhan), China. MD, Medicine, 1992
- Graduate Education
- Tongji Medical University (Wuhan), China. Master of Medical Science, 1995
- Beijing Medical University, China. PhD in Medical Science, 1998
- Junior Faculty Award, American Diabetes Association, 2010
- Research Award, Minnesota Medical Foundation, 2004
- Travel Award, Dept. of BMBB, the University of Minnesota, 2001
- Pilot & Feasibility Research Award, Minnesota Obesity Center, 2002, 2005
- Travel Award, The Center for Diabetes Research, University of Minnesota, 2001
- Courses Taught
- NUTR 470: Nutrition and Physiological Chemistry
- NUTR 681: Nutrition Seminar
The long-term goal of Dr. Wu’s research program is to elucidate the mechanisms underlying the pathogenesis of obesity and overnutrition-associated metabolic diseases including insulin resistance, diabetes, and fatty liver disease so that novel dietary and/or pharmacological approaches can be developed for preventing and/or treating metabolic diseases. Using molecular, cellular, and integrative approaches, the Wu lab is focused on investigating the interaction between metabolism and inflammation.
Obesity, insulin resistance, diabetes, and fatty liver disease
- Wu, N, Meng, F, Zhou, T, Venter, J, Giang, TK, Kyritsi, K et al.. The Secretin/Secretin Receptor Axis Modulates Ductular Reaction and Liver Fibrosis through Changes in Transforming Growth Factor (TGF)-β1-Mediated Biliary Senescence. Am. J. Pathol. 2018; :. doi: 10.1016/j.ajpath.2018.06.015. PubMed PMID:30036520 .
- Zhou, T, Wu, N, Meng, F, Venter, J, Giang, TK, Francis, H et al.. Knockout of secretin receptor reduces biliary damage and liver fibrosis in Mdr2-/- mice by diminishing senescence of cholangiocytes. Lab. Invest. 2018; :. doi: 10.1038/s41374-018-0093-9. PubMed PMID:29977037 .
- Wu, N, McDaniel, K, Zhou, T, Ramos-Lorenzo, S, Wu, C, Huang, L et al.. Knockout of microRNA-21 attenuates alcoholic hepatitis through VHL/NF-κB signaling pathway in hepatic stellate cells. Am. J. Physiol. Gastrointest. Liver Physiol. 2018; :. doi: 10.1152/ajpgi.00111.2018. PubMed PMID:29848019 .